AIMP1 derived protein : Neo-Pep

Neomics Co. Ltd. research toward the developing cosmetic material and pharmaceutical development using the protein derived from Aminoacyl tRNA Synthetase(ARS).
Aminoacyl tRNA synthetase Interacting multifunctional protein 1(AIMP1) is one of the component of ARS-complex(MSC) secreted from diverse mammalian cells. The secreted AIMP1 act as immune reaction, angiogenesis, fibroblast and promote collagen synthesis.

AIMPs functions

Figure 1. Activities of AIMP

A. AIMP1 derived protein : Neo-Pep

AIMP1(aminoacyl tRNA synthetase interacting multifunctional protein 1, p43) is the one of the important component forms the Multi-Synthetase complex(MSC). AIMP1 is secreted from the mammalian cells and can be affect various kind of cell. AIMP1 induce immune reaction and promote endothelial cells to angiogenesis and cell migration. AIMP1 also promotes the fibroblast and collagen synthesis at certain part.

AIMP1 structure

Figure 2. AIMP1 structure

The certain part of AIMP I preforming a specific role is Neo-Pep, AIMP I derived protein. Neo-pep is effective for wound healing through collagen synthesis and fibroblast proliferation in nano molar concentration. Anti-aging process by Neo-pep has already been proved in vivo model. Those features of Neo-Pep have a great potential in the cosmetics industry in relation to anti-aging and skin diseases.